Lidocaine: A Local Anesthetic And Antiarrhythmic Medication
About Lidocaine: Lidocaine or Lignocaine (BAN) is a local anaesthetic agent, which falls under the amide group of local anaesthetics. It is also a class 1-B anti-arrythmic agent, also known as a membrane stabilizing agent. Lidocaine is commonly used in combination with epinephrine or adrenaline, which prolongs the duration of action of Lidocaine. When buffered in solution with sodium bicarbonate, it is much less painful when injected.
How Lidocaine Works: Lidocaine stabilizes the membrane of the neuron, thus preventing the neuronal action potential from occurring and blocking of transmission of pain signals to the brain. It does this by blocking the sodium (Na+) channels of the neuronal membrane, which inhibits depolarization of the cell. The anti-arrythmic action has a similar basis. Lidocaine stabilizes the cardiac cell membrane by interfering with membrane sodium channels and decreasing the excitability of the cell.
How To Take Lidocaine: Lidocaine is available in many forms - as an injectable solution, topical gel, topical spray and even dermal patches. Lidocaine is used as an injectable solution as Lidocaine HCl, its most common form, in local infiltration, regional and surface anaesthesia. Buy Lidocaine is used in concentrations of 0.5%, 1% or 2% with a dosage of 4.5mg/kg (2mg/lb) being the maximum permissible dose of injectable solution. Lidocaine is relatively short acting and is often combined with a longer acting agent such as bupivacaine for a prolonged duration of action. Combination of Lidocaine Without Prescription with epinephrine also achieves this purpose; however, it is not possible to use this combination in certain parts of the body where the use of epinephrine leads to adverse effects. Lidocaine No Prescription is used in the administration of spinal (sub-arachnoid) or epidural anaesthesia in the concentrations of 1%, 1.5% and 2%. The quantity in mL to be injected is decided according the type of regional block being used, as well as the level of dermatome till which the action of Lidocaine is desired. As surface anaesthesia, Buy Lidocaine is used in performing nasal/oral intubations and endoscopies of the gastrointestinal and respiratory tracts. It is used as a topical agent in these situations, taking the form of a spray or a solution. It has also been used as a throat spray to help avoid the gag reflex when performing laryngeal examinations or endoscopies. A topical gel is also available for reducing pain from ulcers and burns. As an anti-arrythmic agent, Buy Lidocaine Without Prescription is used as intravenous injection in the treatment of ventricular arrhythmias occurring after myocardial infarctions, cardioversions or cardiac catherizations.
Precautions And Interactions: Lidocaine No Prescription should be used by only those clinicians who are well versed with its toxicities and adverse effects. It can lead to anaphylactic reactions in susceptible individuals; hence test dose of Lidocaine Without Prescription must be given prior to its use in any patient. This too, must be done in the availability of full resuscitative facilities. Aspiration must be done prior to injection of the solution to avoid inadvertent intra-arterial injection.
Side Effects Of Lidocaine: Allergic reactions due to Lidocaine can range from mild rashes to anaphylaxis. High plasma levels of Lidocaine can lead to cardiologic effects like arrhythmias, hypotension; neurologic effects such as drowsiness, headaches, blurred vision, nausea. These are rarely seen if dose limits of local anaesthesia are followed. Administration of Buy Lidocaine No Prescription in spinal or epidural anaesthesia may lead to positional headaches, hypotension, backache, and rarely, respiratory depression. Lidocaine is a drug with a myriad of uses in every specialty of medicine.